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Vascular Surgery: Current Advances and Future Directions
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Vascular Surgery: Current Advances and Future Directions

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "General Surgery".

Deadline for manuscript submissions: 25 May 2025 | Viewed by 508

Special Issue Editor

Dr. Giovanni Coppi

E-Mail Website
Guest Editor
Department of Vascular and Thoracic Surgery, Bozen Central Hospital, 39100 Bozen, Italy
Interests: vascular surgery; vascular medicine; surgery; aneurysm; stents; endovascular surgery; angioplasty; thoracic surgery; aortic diseases; carotid arteries

Special Issue Information

Dear Colleagues,

Carotid revascularization remains an important part of the everyday practice of a vascular surgery unit. Although much studied with several scientific publications, there are still parts of this topic that remain debated and are not clarified by the most recent guidelines.

The scope of the Special Issue is trying to, according to your personal experience and a thorough review of the literature, shed some light on the more controversial aspects of carotid revascularization. In particular regarding the use of carotid artery stenting in recently symptomatic stenosis, the treatment of tandem intracranial and extracranial carotid stenosis in patients with acute stroke or carotid revascularization after intravenous thrombolysis.

I hope you find this proposal intriguing and could help us write an interesting issue.

Dr. Giovanni Coppi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • stroke
  • carotid artery stenosis
  • carotid artery stenting
  • carotid endarterectomy
  • occlusion

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

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11 pages, 1339 KiB  
Article
Innovative Use of Bleomycin Electrosclerotherapy (BEST) for High-Flow Arteriovenous Malformations in the Head District: Preliminary Results of Two Cases
by Linda Latini, Sandra Bracco, Samuele Cioni, Sara Leonini, Flavia Cascino and Paolo Gennaro
J. Clin. Med. 2025, 14(7), 2516; https://doi.org/10.3390/jcm14072516 (registering DOI) - 7 Apr 2025
Abstract
Background: According to the ISSVA 2018 classification, arteriovenous malformations (AVMs) are high-flow vascular malformations, distinct from low-flow lesions. About 60% of extracranial AVMs occur in the head and neck, making their management a focus of maxillofacial surgery. Due to their complexity, precise [...] Read more.
Background: According to the ISSVA 2018 classification, arteriovenous malformations (AVMs) are high-flow vascular malformations, distinct from low-flow lesions. About 60% of extracranial AVMs occur in the head and neck, making their management a focus of maxillofacial surgery. Due to their complexity, precise diagnosis and careful treatment planning are crucial for optimal aesthetics and structural preservation. The standard approach combines embolization with surgical resection, though Bleomycin electrosclerotherapy (BEST) has recently gained recognition. Methods: From July 2023 to December 2024, a total of 16 patients with vascular malformations were treated with bleomycin electrosclerotherapy at the Azienda Ospedaliera Universitaria Senese (AOUS). Among them, two patients were affected by arteriovenous malformations. These two patients underwent this treatment to avoid more invasive and demolitive procedures, considering the anatomical region involved. Both patients had previously been treated at other hospitals, experiencing subsequent lesion recurrence. Preoperative evaluation included angiographic and ultrasound studies. The patients underwent electrosclerotherapy sessions and were closely monitored during follow-up. The uniqueness of this innovative approach lies in the use of fractionated doses of bleomycin for each treatment session, compared to the standard protocols described in the literature. Results: BEST has demonstrated efficacy in the treatment of high-flow AVMs by delivering bleomycin into the interstitial tissue and subsequently applying electroporation so the drug’s effects can be precisely localized and amplified. The macroscopically evident results, patient satisfaction, and, most importantly, the objective ultrasound flow data demonstrate the effectiveness of this treatment. Conclusions: Arteriovenous malformations (AVMs) pose treatment challenges due to their variability and lack of standardized guidelines. This study explores electrosclerotherapy with bleomycin in two head and neck AVM cases, using fractionated doses to enhance safety and efficacy. The findings support its potential as a minimally invasive alternative, warranting further research on broader applications. Full article
(This article belongs to the Special Issue Vascular Surgery: Current Advances and Future Directions)
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8 pages, 8481 KiB  
Case Report
Limb Salvage in Patients with Concomitant Advanced Malignancy
by Jolyn Hui Qing Pang and Nick Zhi Peng Ng
J. Clin. Med. 2025, 14(5), 1642; https://doi.org/10.3390/jcm14051642 - 28 Feb 2025
Viewed by 222
Abstract
Background: We are experiencing an increasing number of patients presenting with advanced malignancy who are also presenting with chronic limb threatening ischemia. Method: With advancements in medicine and surgery, we are suggesting a shift in mindset of how we treat this [...] Read more.
Background: We are experiencing an increasing number of patients presenting with advanced malignancy who are also presenting with chronic limb threatening ischemia. Method: With advancements in medicine and surgery, we are suggesting a shift in mindset of how we treat this group of patients and proposing a more holistic approach for treatment options. Result: In this original article, we highlight our approach in managing such patients and suggest an algorithm. Conclusions: We hope that our article brings awareness and assists vascular surgeons in managing such cases, resulting in improved quality of life for these patients. Full article
(This article belongs to the Special Issue Vascular Surgery: Current Advances and Future Directions)
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