Journal Description
Healthcare
Healthcare
is an international, scientific, peer-reviewed, open access journal on health care systems, industry, technology, policy, and regulation, and is published semimonthly online by MDPI. European Medical Association (EMA) and Ocular Wellness & Nutrition Society (OWNS) are affiliated with Healthcare and their members receive discounts on the article processing charges.
- Open Access— free for readers, with article processing charges (APC) paid by authors or their institutions.
- High Visibility: indexed within Scopus, SCIE and SSCI (Web of Science), PubMed, PMC, and other databases.
- Journal Rank: JCR - Q2 (Health Care Sciences and Services) / CiteScore - Q2 (Leadership and Management)
- Rapid Publication: manuscripts are peer-reviewed and a first decision is provided to authors approximately 20.3 days after submission; acceptance to publication is undertaken in 2.6 days (median values for papers published in this journal in the second half of 2024).
- Recognition of Reviewers: reviewers who provide timely, thorough peer-review reports receive vouchers entitling them to a discount on the APC of their next publication in any MDPI journal, in appreciation of the work done.
- Companion journals for Healthcare include: Trauma Care and European Burn Journal.
Impact Factor:
2.4 (2023);
5-Year Impact Factor:
2.5 (2023)
Latest Articles
The Role of Neuroinflammation in the Comorbidity of Psychiatric Disorders and Internal Diseases
Healthcare 2025, 13(7), 837; https://doi.org/10.3390/healthcare13070837 (registering DOI) - 7 Apr 2025
Abstract
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Psychiatric disorders and internal diseases frequently co-occur, posing significant challenges due to overlapping symptoms, shared pathophysiological mechanisms, and increased healthcare burdens. Neuroinflammation has emerged as a central mechanism linking these conditions, driven by systemic inflammation, hypothalamic–pituitary–adrenal (HPA) axis dysregulation, and autonomic nervous system
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Psychiatric disorders and internal diseases frequently co-occur, posing significant challenges due to overlapping symptoms, shared pathophysiological mechanisms, and increased healthcare burdens. Neuroinflammation has emerged as a central mechanism linking these conditions, driven by systemic inflammation, hypothalamic–pituitary–adrenal (HPA) axis dysregulation, and autonomic nervous system (ANS) imbalance. This review synthesizes current evidence on the role of neuroinflammation in comorbid conditions such as depression, anxiety, cardiovascular disease, and diabetes mellitus, emphasizing bidirectional relationships and shared inflammatory pathways. This analysis identifies gaps in longitudinal studies, biomarker validation, and the integration of multidisciplinary care models. Emerging therapeutic approaches, including IL-6 inhibitors, vagus nerve stimulation, and behavioral interventions, show promise but remain underexplored in combined applications. Furthermore, disparities in research representation limit the generalizability of findings and highlight the need for inclusive clinical trials. Addressing these gaps through precision medicine, advanced biomarker monitoring technologies, and equitable healthcare strategies could transform the management of these complex comorbidities. By advancing our understanding of neuroinflammatory mechanisms and promoting integrated interventions, this review underscores the need for a collaborative, patient-centered approach to improve outcomes and reduce the global burden of psychiatric and internal disease comorbidities.
Full article
Open AccessArticle
Assessing Patient Satisfaction with Hospital Services: Perspectives from Bihor County Emergency Hospital, Romania
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Aliz Ildiko Bradács, Florica Voiță-Mekeres, Lucia Georgeta Daina, Lavinia Davidescu and Călin Tudor Hozan
Healthcare 2025, 13(7), 836; https://doi.org/10.3390/healthcare13070836 (registering DOI) - 7 Apr 2025
Abstract
Background/Objectives: The objective of this study is to assess overall patient satisfaction with hospital services, including cleanliness, ward conditions, and food quality. Another key goal is to determine patient willingness to return for future medical services and identify the factors influencing this decision.
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Background/Objectives: The objective of this study is to assess overall patient satisfaction with hospital services, including cleanliness, ward conditions, and food quality. Another key goal is to determine patient willingness to return for future medical services and identify the factors influencing this decision. Moreover, the study explores the relationship between patient satisfaction and continuity of care, as indicated by previous hospitalizations. Methods: We conducted a retrospective cohort study to evaluate patient satisfaction at the Bihor County Emergency Clinical Hospital in Oradea, Romania. A standardized 40-item questionnaire was developed in accordance with the Framework Agreement on the provision of medical assistance within the Romanian healthcare system. The survey, which was administered over a four-year period (2019–2022), covered seven domains: demographic data, accessibility, hotel conditions, quality of care, patient safety and rights, overall satisfaction, and feedback. A total of 12,802 patients completed the questionnaire, and all statistical analyses were performed using R Studio. Results: This study analyzes patient-reported satisfaction and experiences in a large healthcare facility, based on data from 12,802 participants. Overall, 91% of respondents rated the hospital positively, with 62% giving an excellent score. Spiritual assistance was well received (71%), and 70% of patients expressed willingness to return for future medical needs. Hospital cleanliness and ward conditions were rated highly, with 71% of respondents reporting excellent experiences. Food quality was positively reviewed by 66% of participants. Most patients (95%) confirmed proper hygiene practices by medical staff, and 95% were informed about their diagnosis. However, only 67% were aware of the complaint submission process. The dataset spans 2019–2022, with the highest hospitalizations in 2020 (36%) and obstetrics, cardiology, and general surgery being the most common specialties. Conclusions: This dataset reflects a high level of patient satisfaction across multiple dimensions of hospital services, including cleanliness, quality of care, and patient information. However, areas such as complaint handling and transparency in medication handling require further attention to improve the overall patient experience. The findings underscore the hospital’s strong performance in meeting patient expectations while identifying key areas for continued improvement.
Full article
(This article belongs to the Special Issue Health Promotion, Disease Prevention, and Chronic Illness Experience: A Health Psychology Perspective)
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Open AccessBrief Report
Can ChatGPT Help General Practitioners Become Acquainted with Conversations About Dying? A Simulated Single-Case Study
by
Filipe Prazeres
Healthcare 2025, 13(7), 835; https://doi.org/10.3390/healthcare13070835 (registering DOI) - 6 Apr 2025
Abstract
Background/Objectives: General practitioners (GPs) should be able to initiate open conversations about death with their patients. It is hypothesized that a change in attitude regarding discussions of death with patients may be accomplished through doctors’ training, particularly with the use of artificial
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Background/Objectives: General practitioners (GPs) should be able to initiate open conversations about death with their patients. It is hypothesized that a change in attitude regarding discussions of death with patients may be accomplished through doctors’ training, particularly with the use of artificial intelligence (AI). This study aimed to evaluate whether OpenAI’s ChatGPT can simulate a medical communication scenario involving a GP consulting a patient who is dying at home. Methods: ChatGPT-4o was prompted to generate a medical communication scenario in which a GP consults with a patient dying at home. ChatGPT-4o was instructed to follow seven predefined steps from an evidence-based model for discussing dying with patients and their family caregivers. The output was assessed by comparing each step of the conversation to the model’s recommendations. Results: ChatGPT-4o created a seven-step scenario based on the initial prompt and addressed almost all intended recommendations. However, two points were not addressed: ChatGPT-4o did not use terms like “dying”, “passing away”, or “death”, although the concept was present from the beginning of the conversation with the patient. Additionally, cultural and religious backgrounds related to dying and death were not discussed. Conclusions: ChatGPT-4o can be used as a supportive tool for introducing GPs to the language and sequencing of speech acts that form a successful foundation for meaningful, sensitive conversations about dying, without requiring advanced technical resources and without placing any burden on real patients.
Full article
(This article belongs to the Special Issue Improving the Quality of Nursing: Focus on Palliative Care and End-of-Life Care)
Open AccessPerspective
The Pharmacists of Physical Activity: Physiotherapists Empowering Older Adults’ Autonomy in the Self-Management of Aging with and Without Persistent Conditions
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Mike Studer, Kent Edward Irwin and Mariana Wingood
Healthcare 2025, 13(7), 834; https://doi.org/10.3390/healthcare13070834 (registering DOI) - 6 Apr 2025
Abstract
Aging has been thought to be factual, inherited, and obligatory. However, aging can be divided into primary (i.e., inevitable physiological changes) and secondary (i.e., age-associated changes driven by life choices, environment, and society) aging. The impact of social norms and life choices is
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Aging has been thought to be factual, inherited, and obligatory. However, aging can be divided into primary (i.e., inevitable physiological changes) and secondary (i.e., age-associated changes driven by life choices, environment, and society) aging. The impact of social norms and life choices is why no two 70-year-olds look the same. The life choice that appears to have the strongest impact on aging is physical activity. Research continues to highlight the power of mitigating age-related losses via physical activity and debunking the notion that age-related changes such as falls, frailty, and functional decline are inevitable. Physiotherapists are the healthcare professionals who reverse or slow down age-related changes and prevent secondary aging from occurring. Physiotherapists are the health profession’s experts in movement science, whose interventions primarily center around physical activity as medicine. Thus, physiotherapists function as pharmacists of physical activity and are well-positioned to prescribe the dosages needed for wellness promotion as well as disease prevention and management. This paper provides guidance from the perspective of the physiotherapist on exercise prescription most optimal and consumable for an older population.
Full article
(This article belongs to the Special Issue Role of Physiotherapy in Promoting Physical Activity and Well-Being)
Open AccessArticle
Maternal Health Risk Detection: Advancing Midwifery with Artificial Intelligence
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Katerina D. Tzimourta, Markos G. Tsipouras, Pantelis Angelidis, Dimitrios G. Tsalikakis and Eirini Orovou
Healthcare 2025, 13(7), 833; https://doi.org/10.3390/healthcare13070833 (registering DOI) - 6 Apr 2025
Abstract
Background/Objectives: Maternal health risks remain one of the critical challenges in the world, contributing much to maternal and infant morbidity and mortality, especially in the most vulnerable populations. In the modern era, with the recent progress in the area of artificial intelligence
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Background/Objectives: Maternal health risks remain one of the critical challenges in the world, contributing much to maternal and infant morbidity and mortality, especially in the most vulnerable populations. In the modern era, with the recent progress in the area of artificial intelligence and machine learning, much promise has emerged with regard to achieving the goal of early risk detection and its management. This research is set out to relate high-risk, low-risk, and mid-risk maternal health using machine learning algorithms based on physiological data. Materials and Methods: The applied dataset contains 1014 instances (i.e., cases) with seven attributes (i.e., variables), namely, Age, SystolicBP, DiastolicBP, BS, BodyTemp, HeartRate, and RiskLevel. The preprocessed dataset used was then trained and tested with six classifiers using 10-fold cross-validation. Finally, the performance metrics of the models erre compared using metrics like Accuracy, Precision, and the True Positive Rate. Results: The best performance was found for the Random Forest, also reaching the highest values for Accuracy (88.03%), TP Rate (88%), and Precision (88.10%), showing its robustness in handling maternal health risk classification. The mid-risk category was the most challenging across all the models, characterized by lowered Recall and Precision scores, hence underlining class imbalance as one of the bottlenecks in performance. Conclusions: Machine learning algorithms hold strong potential for improving maternal health risk prediction. The findings underline the place of machine learning in advancing maternal healthcare by driving more data-driven and personalized approaches.
Full article
(This article belongs to the Special Issue Interdisciplinary Perspectives in Maternal Health: Integrating Theoretical Frameworks and Practical Applications)
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Open AccessArticle
How to Assess Health Gains
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Giovanni Guarducci, Gabriele Messina, Chiara Siragusa, Jolanda Gurnari, Anna Maria Gentile and Nicola Nante
Healthcare 2025, 13(7), 832; https://doi.org/10.3390/healthcare13070832 (registering DOI) - 5 Apr 2025
Abstract
Background/Objectives: As life expectancy rises and the epidemiological landscape of chronic diseases evolves, the necessity to assess and improve the overall health status of the population becomes increasingly fundamental. Therefore, evaluating health gains is a crucial challenge for modern health systems, particularly
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Background/Objectives: As life expectancy rises and the epidemiological landscape of chronic diseases evolves, the necessity to assess and improve the overall health status of the population becomes increasingly fundamental. Therefore, evaluating health gains is a crucial challenge for modern health systems, particularly in the context of limited resources and increasing demand for services. The aim of this study is to assess health gains and their costs, with data provided by a private Italian clinic. Methods: We conducted a retrospective study on 129 patients admitted between June 2020 and August 2023 in a solvent ward for short-term planned hospitalization. The patients completed the EQ-5D-5L questionnaire at both admission and discharge. Quality-Adjusted Life Years (QALYs) were estimated based on the difference in EQ-5D-5L scores between discharge and admission, assuming that health gains persist up to two years post-discharge. Through QALYs value and hospitalization cost, a cost–utility analysis was performed. Descriptive and statistical analyses were carried out using STATA SE/14.0 software. Results: Of the studied sample, 55% was female, the median age was 81 [11] years old, and the median length of stay (LoS) was 16 [16] days. The patients gained, in median, 0.33 [0.38] in QALY, which was higher for males (0.35 [0.34]) than females (0.29 [0.45]). The QALY gained was greater for the non-geriatric patients (0.41 [0.42]) than geriatric ones (0.32 [0.38]) (p > 0.05). Those with a longer LoS showed a higher gain in QALY (0.35 [0.42]) than those with a shorter one (0.23 [0.29]) (p < 0.05). The cost per QALY gained was, in median, EUR 14,337, which was lower in males (EUR 13,803), in non-geriatric patients (EUR 13,743), and in patients with a shorter LoS (EUR 10,670) (p > 0.05). Conclusions: Although QALY gains differed among the groups, the median cost per QALY remained consistent. These results highlight the need for targeted interventions to optimize resource allocation, both by integrating data into allocation strategies and by employing a multidisciplinary approach to tailor interventions.
Full article
(This article belongs to the Special Issue Patient Experience and the Quality of Health Care)
Open AccessArticle
Breaking the Silence: Barriers to Error Disclosure Among Nurses in the Kingdom of Saudi Arabia—A Cross-Sectional Study
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Naglaa Abdelaziz Mahmoud Elseesy, Budoor Ahmad Almezraq, Duaa Amr Hafez, Ohood Felemban and Ebaa Marwan Felemban
Healthcare 2025, 13(7), 831; https://doi.org/10.3390/healthcare13070831 (registering DOI) - 5 Apr 2025
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Background: Medical errors are common, and in particular, medication errors are one of the leading causes of morbidity and mortality in healthcare. Nurses must disclose errors to build trust and ensure patient safety despite communication barriers and fear of reprisals. Truthful documentation and
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Background: Medical errors are common, and in particular, medication errors are one of the leading causes of morbidity and mortality in healthcare. Nurses must disclose errors to build trust and ensure patient safety despite communication barriers and fear of reprisals. Truthful documentation and better collaboration can improve patient outcomes. Aim: The aim of this study was to assess barriers to error disclosure among nurses in the Kingdom of Saudi Arabia. Methods: A descriptive cross-sectional survey was conducted in the months of June and August 2024 using a convenience sample of 255 nurses at King Fahad Hospital (KFH), Hofuf. A self-administered questionnaire that contained socio-demographic questions, as well as the Barriers to Error Disclosure Assessment (BEDA) tool, was deployed. Results: The majority of the sample were female (92.2%) and Bachelor’s degree holders (80.8%) who had 1–5 or 6–10 years of experience, representing 45.5% and 29.0% of the sample, respectively. When medical errors occur, only 18% of the nurses disclosed them to patients and their families, and 34.5% of the respondents disclosed medical errors to another team of healthcare professionals. The types of barriers to error disclosure were identified as relating to confidence and knowledge barriers, institutional barriers, psychological barriers, and financial concern barriers. The overall barrier score had an average of 63%. The barriers with the highest scores were those relating to psychological barriers (68.2%), followed by institutional barriers (66.5%) and financial concern barriers (64.5%). Conclusions: Targeted interventions are required for addressing the identified specific needs to support healthcare providers, specifically nurses. New regulations and policy changes are crucial for training programs implementation, enhancing safety culture, and tackling job-related insecurities to minimize barriers to error disclosure and ultimately provide better patient care quality. Further investigations may include a different approach, and it is recommended to provide deeper insights into nurse experiences.
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Open AccessCase Report
Lost in Transition: Challenges in the Journey from Pediatric to Adult Care for a Romanian DMD Patient
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Maria Lupu, Maria-Alexandra Marcu, Diana Anamaria Epure, Oana Aurelia Vladacenco, Emilia Maria Severin and Raluca Ioana Teleanu
Healthcare 2025, 13(7), 830; https://doi.org/10.3390/healthcare13070830 (registering DOI) - 5 Apr 2025
Abstract
Background: The transition from pediatric to adult care in Duchenne Muscular Dystrophy (DMD) is challenging due to the disease’s complexity and the need for lifelong, comprehensive management. In Romania, ongoing efforts aim to enhance multidisciplinary collaboration, though systemic barriers, such as
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Background: The transition from pediatric to adult care in Duchenne Muscular Dystrophy (DMD) is challenging due to the disease’s complexity and the need for lifelong, comprehensive management. In Romania, ongoing efforts aim to enhance multidisciplinary collaboration, though systemic barriers, such as fragmented healthcare services, persist. Nonsense mutations, including those in exon 30 described here, are often associated with more severe disease progression. Methods: We present the case of a 17-year-old Romanian DMD patient with a nonsense mutation in exon 30 of the dystrophin gene. The patient received multidisciplinary pediatric care addressing his medical needs, including neuromuscular, respiratory, cardiac, and orthopedic management. Transition readiness was assessed using the Transition Readiness Assessment Questionnaire (TRAQ), and the patient’s perspective on the process was documented. Results: Care followed international standards, but the disease progressed predictably, with gradual loss of ambulation, respiratory decline, and cardiac complications. The TRAQ revealed strengths in communication with healthcare providers but moderate confidence in self-management tasks. From the patient’s perspective, fragmented adult services and difficulty accessing specialized neuromuscular support remain major obstacles, underscoring the importance of early, structured transition planning and patient-centered approaches. Conclusions: Transitioning to adult services requires strong communication between pediatric and adult teams and integration of specialized care. Tailored follow-up plans ensure continuity of care and effective disease management. This case reflects broader needs in similar healthcare contexts, highlighting the necessity of robust transition frameworks to respond to patient-specific challenges and ultimately support long-term quality of life.
Full article
(This article belongs to the Special Issue Health Service Interventions in Musculoskeletal Disorders)
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Ethical, Legal, and Social Assessment of AI-Based Technologies for Prevention and Diagnosis of Rare Diseases in Health Technology Assessment Processes
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Pietro Refolo, Costanza Raimondi, Violeta Astratinei, Livio Battaglia, Josep M. Borràs, Paula Closa, Alessandra Lo Scalzo, Marco Marchetti, Sonia Muñoz-López, Laura Sampietro-Colom and Dario Sacchini
Healthcare 2025, 13(7), 829; https://doi.org/10.3390/healthcare13070829 (registering DOI) - 4 Apr 2025
Abstract
Background: While the HTA community appears well-equipped to assess preventive and diagnostic technologies, certain limitations persist in evaluating technologies designed for rare diseases, including those based on Artificial Intelligence (AI). In Europe, the EUnetHTA Core Model® serves as a reference for assessing
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Background: While the HTA community appears well-equipped to assess preventive and diagnostic technologies, certain limitations persist in evaluating technologies designed for rare diseases, including those based on Artificial Intelligence (AI). In Europe, the EUnetHTA Core Model® serves as a reference for assessing preventive and diagnostic technologies. This study aims to identify key ethical, legal, and social issues related to AI-based technologies for the prevention and diagnosis of rare diseases, proposing enhancements to the Core Model. Methods: An exploratory sequential mixed methods approach was used, integrating a PICO-guided literature review and a focus group. The review analyzed six peer-reviewed articles and compared the findings with a prior study on childhood melanoma published in this journal (Healthcare), retaining only newly identified issues. A focus group composed of experts in ethical, legal, and social domains provided qualitative insights. Results: Thirteen additional issues and their corresponding questions were identified. Ethical concerns related to rare diseases included insufficient disease history knowledge, lack of robust clinical data, absence of validated efficacy tools, overdiagnosis/underdiagnosis risks, and unknown ICER thresholds. Defensive medicine was identified as a legal issue. For AI-based technologies, concerns included discriminatory outcomes, explicability, and environmental impact (ethical); accountability and reimbursement (legal); and patient involvement and job losses (social). Conclusions: Integrating these findings into the Core Model enables a comprehensive HTA of AI-based rare disease technologies. Beyond the Core Model, these issues may inform broader assessment frameworks, ensuring rigorous and ethically responsible evaluations.
Full article
(This article belongs to the Special Issue Advances in Health Technology Assessment in the Era of AI and Data Science)
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Open AccessSystematic Review
Towards the Identification of Patients’ Needs for Promoting Robotics and Allied Digital Technologies in Rehabilitation: A Systematic Review
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Alessio Fasano, Maria Cristina Mauro, Elena Beani, Giovanna Nicora, Marco Germanotta, Francesca Falchini, Arianna Pavan, Valeria Habib, Silvana Quaglini, Giuseppina Sgandurra and Irene Giovanna Aprile
Healthcare 2025, 13(7), 828; https://doi.org/10.3390/healthcare13070828 (registering DOI) - 4 Apr 2025
Abstract
Background/Objectives: Robotic rehabilitation holds great potential for improving patient outcomes, but the integration of these technologies into clinical practice is hindered by a lack of comprehensive tools for assessing patients’ needs. This systematic review aimed to identify gaps in the current literature,
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Background/Objectives: Robotic rehabilitation holds great potential for improving patient outcomes, but the integration of these technologies into clinical practice is hindered by a lack of comprehensive tools for assessing patients’ needs. This systematic review aimed to identify gaps in the current literature, with a focus on methodologies and tools for evaluating such needs, particularly those based on the International Classification of Functioning, Disability, and Health (ICF) framework. Methods: A systematic review of qualitative studies published between 2021 and 2023 was conducted, updating a previous (2020) review. Studies were identified through PubMed, Scopus, and Web of Science using inclusion criteria focused on qualitative methods capturing patients’ experiences with robotic and technological rehabilitation devices. Results: The review analyzed 19 new studies and 20 from the prior review, revealing a reliance on semi-structured interviews targeting small, heterogeneous populations. No studies employed standardized ICF-based tools, and gaps were noted in the exploration of conditions such as Parkinson’s disease, frailty, or conditions that allowed for multi-device experiences. Conclusions: The findings emphasize the necessity for tailored surveys grounded in the ICF framework to completely evaluate the needs of patients suffering from sensory, motor, and/or cognitive disorders caused by different health conditions. This work lays the foundation for more inclusive, effective, and patient-centered robotic rehabilitation strategies.
Full article
(This article belongs to the Special Issue Assistive Technologies, Robotics, and Automated Machines in the Health Domain: Second Edition)
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Open AccessArticle
The Impact of Mental Health Comorbidities on Unplanned Admissions for Physical Conditions: A Retrospective Observational Analysis
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Fabrizio Cedrone, Omar Enzo Santangelo, Vittorio Di Michele, Alessandro Catalini, Flavia Pennisi, Lorenzo Stacchini, Marco Fonzo, Vincenzo Montagna, Vincenza Gianfredi and Giuseppe Di Martino
Healthcare 2025, 13(7), 827; https://doi.org/10.3390/healthcare13070827 (registering DOI) - 4 Apr 2025
Abstract
Background: This study aimed to evaluate the impact of mental health comorbidities on unplanned hospital admissions (UHAs) in the Province of Pescara, Southern Italy, during 2015–2022. Mental health comorbidities are underreported in administrative data, yet their association with UHAs has significant public
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Background: This study aimed to evaluate the impact of mental health comorbidities on unplanned hospital admissions (UHAs) in the Province of Pescara, Southern Italy, during 2015–2022. Mental health comorbidities are underreported in administrative data, yet their association with UHAs has significant public health implications. Methods: A retrospective observational design was used to analyze 59,374 hospital admissions extracted from hospital discharge records (HDRs). Admissions of patients under 18 years of age, deliveries, day admissions, and readmissions were excluded. Socio-economic deprivation was assessed using a standardized deprivation index. Multivariate logistic regression analyzed the association between UHAs and mental health comorbidities, adjusting for socio-demographic and clinical factors. Results: Of the 59,374 admissions, 43,293 (72.9%) were unplanned. Mental health comorbidities had a low prevalence (1552 cases, 2.6%) but were significantly more common in UHAs (3.4%) compared to planned admissions (0.4%, p < 0.001). UHAs were also associated with the female gender (OR = 1.10; 95% CI: 1.06–1.14), younger age categories, living in less deprived areas, two or more physical comorbidities (OR = 1.66; 95% CI: 1.56–1.75), and mental health comorbidities (aOR = 9.85; 95% CI: 7.74–12.55, p < 0.001). Conclusions: Mental health comorbidities significantly increase the risk of UHAs independent of socio-economic deprivation or physical comorbidities. These findings underscore the need for enhanced mental health management to reduce UHAs, improve patient outcomes, and address healthcare inequities.
Full article
(This article belongs to the Special Issue Perspectives on Primary and Community Healthcare)
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Open AccessReview
Effectiveness of Telecoaching and Music Therapy in Neurological Disorders: A Narrative Review and Proposal for a New Interventional Approach
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Ignazio Leale, Claudia Vinciguerra, Vincenzo Di Stefano, Filippo Brighina and Giuseppe Battaglia
Healthcare 2025, 13(7), 826; https://doi.org/10.3390/healthcare13070826 (registering DOI) - 4 Apr 2025
Abstract
Neurological disorders represent a significant challenge for healthcare systems, necessitating innovative and multidisciplinary therapeutic approaches. These disorders often lead to difficulties in various aspects of daily life, including physical functioning, mental health, and quality of life (QoL). Telecoaching (TC) and Music Therapy (MT)
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Neurological disorders represent a significant challenge for healthcare systems, necessitating innovative and multidisciplinary therapeutic approaches. These disorders often lead to difficulties in various aspects of daily life, including physical functioning, mental health, and quality of life (QoL). Telecoaching (TC) and Music Therapy (MT) are two emerging modalities that may provide valuable support for individuals with these conditions. This narrative review aims to analyse recent studies investigating the efficacy of TC and MT in this population. A total of 23 studies were included in this narrative review. These studies indicate that TC positively affects physical functioning and adherence to intervention programs, with participants reporting improvements in gait and balance, as well as a reduction in postural instability and fall rates. Similarly, MT has shown promising outcomes in decreasing anxiety and sleep disorders while enhancing cognitive and emotional well-being. Integrating TC and MT into treatment approaches offers a promising alternative for improving QoL and overall well-being. However, further research is needed to consolidate the evidence and optimize the implementation of these interventions in clinical practice. Future research should focus on longitudinal studies and comparative evaluations to further clarify the role of TC and MT in the treatment of neurological disorders, as well as their long-term effects.
Full article
(This article belongs to the Special Issue Music Therapy and Physical Activity in Neurological Diseases)
Open AccessArticle
COPSOQ III in China: Preliminary Validation of an International Instrument to Measure Psychosocial Work Factors
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Yiming Huang, Min Zhang, Fuyuan Wang, Yuting Tang, Chuning He, Xinxin Fang and Xuechun Wang
Healthcare 2025, 13(7), 825; https://doi.org/10.3390/healthcare13070825 (registering DOI) - 4 Apr 2025
Abstract
Background: The Copenhagen Psychosocial Questionnaire (COPSOQ) is an international instrument designed for the assessment and improvement of psychosocial conditions in workplaces and for research purposes. After the International COPSOQ Network took over responsibility for the development of COPSOQ, a new version was published
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Background: The Copenhagen Psychosocial Questionnaire (COPSOQ) is an international instrument designed for the assessment and improvement of psychosocial conditions in workplaces and for research purposes. After the International COPSOQ Network took over responsibility for the development of COPSOQ, a new version was published in 2019 (COPSOQ III). However, there is no widely recognized instrument for measuring psychosocial work factors, and insufficient research exists regarding the use of COPSOQ III within the Chinese setting. This study seeks to conduct a preliminary validation of the Chinese long version of COPSOQ III. Methods: A cross-sectional questionnaire survey was conducted with a large sample in a medical consortium in China. Item analysis, reliability, and validity were explored. Results: The data management platform showed that 1067 respondents who met the inclusion criteria completed the questionnaire, among which 1054 questionnaires were valid. The content validity results showed that the I-CVI and S-CVI/AVE of each item ranged from 42.86 to 100.00, and the S-CVI/AVE was 92.52, indicating that the Chinese long version of COPSOQ III had good content validity. An exploratory factor analysis (EFA) extracted seven factors, which explained 63.96% of the variation. The results of confirmatory factor analysis (CFA) indicated that the model was well fit (χ2/df = 4.50, CFI = 0.910, TLI = 0.897, IFI = 0.910, RMSEA = 0.058). The Cronbach alpha coefficient of the questionnaire was 0.92. Conclusions: The Chinese long version of COPSOQ III is of good reliability and validity, like the original, and can be used to assess psychosocial work factors in China.
Full article
Open AccessArticle
Accelerating the Delivery of Psychological Therapies After Stroke: A Feasibility Stepped-Wedge Cluster Randomised Controlled Trial
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C. Elizabeth Lightbody, Kulsum Patel, Emma-Joy Holland, Chris J. Sutton, Christopher Brown, Svetlana V. Tishkovskaya, Audrey Bowen, Jessica Read, Shirley Thomas, Temitayo Roberts and Caroline L. Watkins
Healthcare 2025, 13(7), 824; https://doi.org/10.3390/healthcare13070824 (registering DOI) - 4 Apr 2025
Abstract
Background: Psychological problems post-stroke are common and debilitating, yet insufficient evidence-based psychological support exists for stroke survivors, either in stroke or general mental health services. Many stroke survivors with significant needs remain unsupported. To address this problem, we need pathways to identify, treat
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Background: Psychological problems post-stroke are common and debilitating, yet insufficient evidence-based psychological support exists for stroke survivors, either in stroke or general mental health services. Many stroke survivors with significant needs remain unsupported. To address this problem, we need pathways to identify, treat and manage psychological difficulties after stroke. The Accelerating Delivery of Psychological Therapies after Stroke (ADOPTS) study aimed to explore the feasibility of collaboratively developing, implementing and evaluating intervention packages (IPs) to facilitate access to, and increase the provision of, psychological support post-stroke. Methods: Stakeholder groups were formed across four sites in north-west England, comprising stroke and psychological services, to collaboratively develop site-specific IPs incorporating a psychological care pathway, staff training, a staff manual for stroke-specific psychological support and supervision. A feasibility stepped-wedge cluster randomised trial recruited patients admitted with stroke during the usual care (pre-implementation of the IP) and intervention (post-implementation) periods. The feasibility of IP implementation and their potential usefulness were evaluated through assessing wellbeing and the support received, and through a process evaluation incorporating interviews with staff, patients and carers. Feasibility evaluation included the recruitment rate and attrition rate; exploratory analysis (mixed-effects linear or logistic regression models) was used to assess the ‘promise’ of the intervention in achieving psychological distress outcomes (mood (PHQ-9), anxiety (GAD-7)), assessed using validated measures at 6 weeks and 6 months. Results: IPs were collaboratively developed at each site but implementation took longer than the per-study-protocol duration of three months. Nineteen training sessions (152 attendees) were delivered for nursing, therapy, NHS Talking Therapies and voluntary staff. Nursing staff were underrepresented due to difficulties with releasing staff. Manuals were developed for each site, incorporating a mood screening and referral algorithm, but these were not finalised at one site. Stroke and NHS Talking Therapies champions were identified in each site to facilitate cross-service staff supervision. A total of 270 patients were recruited over 14 months (133 usual care, 137 intervention), with 227 and 198 at 6 weeks and 6 months, respectively. Stroke staff found the training, manual and pathway helpful, and reported greater confidence in managing and referring psychological issues. NHS Talking Therapies staff found the training useful for adapting their therapy. However, the intervention took longer to implement in all sites, requiring an additional time period to be added to the stepped-wedge design. Conclusions: It is feasible to collaboratively develop and implement IPs for post-stroke psychological support. However, an alternative to the stepped-wedge design used here would be more appropriate for a future study. This study was registered in ISRCTN—the UK’s Clinical Study Registry (trial registration: ISRCTN12868810, registration date: 4 February 2016).
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(This article belongs to the Special Issue Stroke and Ageing)
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Open AccessArticle
The Role of Gender in the Relationship Between Waist-to-Hip Ratio, Triglyceride–Glucose Index, and Insulin Resistance in Korean Children
by
Seamon Kang, Xiaoming Qiu, Simon Kim and Hyunsik Kang
Healthcare 2025, 13(7), 823; https://doi.org/10.3390/healthcare13070823 (registering DOI) - 4 Apr 2025
Abstract
Background/Objectives: Little is known about the relationship between obesity, the triglyceride–glucose (TyG) index, and insulin resistance (IR). This cross-sectional study of Korean children investigated whether the TyG index mediates the relationship between the waist-to-hip ratio (WHtR) and homeostatic model assessment for IR (HOMA-IR).
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Background/Objectives: Little is known about the relationship between obesity, the triglyceride–glucose (TyG) index, and insulin resistance (IR). This cross-sectional study of Korean children investigated whether the TyG index mediates the relationship between the waist-to-hip ratio (WHtR) and homeostatic model assessment for IR (HOMA-IR). Methods: Six-hundred-and-thirteen Korean children (320 boys and 293 girls) aged 9–12 years old participated in this study. The participants were classified as insulin-sensitive or insulin-resistant based on gender-specific cut-off values of HOMA-IR. The TyG index was calculated as follows: ln [fasting triglycerides (mg/dL) × fasting blood glucose (mg/dL)/2]. Results: Children with IR were older, more likely to be girls, and had fewer favorable metabolic risk factors than children without IR. A mediation analysis revealed that while WHtR has a direct effect on HOMA-IR, it also has an indirect effect on HOMA-IR through the TyG index. The bootstrapped 95% confidence interval (CI) confirmed that the TyG index had an indirect effect on the relationship between the WHtR and HOMA-IR (effect = 0.349, SE = 0.075, 95% CI [0.210, 0.504]). The interaction effect between the WHtR and sex for the TyG index was statistically significant (β = −1.369, SE = 0.631, 95% CI [−2.608, −0.129]), but it was no longer significant when vigorous physical activity was considered as a covariate. Conclusions: Our findings suggest that girls are more vulnerable than boys to an increase in the TyG index caused by an increase in WHtR. This gender disparity observed in the study needs to be investigated causally.
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(This article belongs to the Special Issue Obesity and Metabolic Abnormalities)
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Open AccessArticle
A Qualitative Study Exploring the Rehabilitation Experience of Individuals with a Previous Diagnosis of Cancer and/or Sepsis, Their Caregivers, and Health Providers
by
Jenna Smith-Turchyn, Christopher Farley, Anastasia N. L. Newman, Jayden Pannu, Bram Rochwerg, Som D. Mukherjee, Marla Beauchamp, Linda C. Li, Hira Mian and Michelle E. Kho
Healthcare 2025, 13(7), 822; https://doi.org/10.3390/healthcare13070822 (registering DOI) - 4 Apr 2025
Abstract
Background/Objectives: Survivors of cancer have more than double the risk of developing sepsis compared to those with no history of cancer. Those who develop sepsis have lasting side effects reducing their physical function and quality of life. Rehabilitation-related needs and barriers are unknown
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Background/Objectives: Survivors of cancer have more than double the risk of developing sepsis compared to those with no history of cancer. Those who develop sepsis have lasting side effects reducing their physical function and quality of life. Rehabilitation-related needs and barriers are unknown for individuals with cancer who have had sepsis. The aim of this study was to examine the rehabilitation-related experiences of patients with cancer and/or sepsis, their caregivers, and the healthcare team and the educational needs regarding the rehabilitation of patients with sepsis. Methods: We performed a qualitative descriptive study using interviews and focus groups for data generation. We included adults living in Canada who were English-speaking, currently or formerly diagnosed with cancer and/or sepsis, or a caregiver of someone with a current or past diagnosis of cancer and/or sepsis, or a healthcare professional working with this population. Two reviewers used NVivo software for data management and conducted a qualitative data analysis. Results: We included 30 study participants (nine patients, nine caregivers, 12 healthcare professionals; 15 for one-on-one interviews; 15 in the focus groups). We identified three overarching themes relating to rehabilitation: (1) the rehabilitation experience did not meet the patient’s care expectations; (2) barriers to rehabilitation exist on multiple levels; (3) there are important gaps in education on how to improve physical and psychosocial outcomes. We identified two themes related to educational resources: (1) the educational content provided must be specific and meaningful; (2) multi-modal resources are needed to suit diverse partner needs. Conclusions: We identified rehabilitation barriers related to healthcare settings, the pandemic, and workplace culture for those with cancer and sepsis. This study highlights the need to create diverse educational resources on rehabilitation for those with sepsis to improve outcomes and patient/caregiver satisfaction.
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(This article belongs to the Special Issue Health Promotion, Disease Prevention, and Chronic Illness Experience: A Health Psychology Perspective)
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Open AccessArticle
Addressing Bureaucratic Burdens on the Portuguese National Health Service: A Simplification Experience Aiming for Value-Based Healthcare
by
Francisco Goiana-da-Silva, Raisa Guedes, Filipa Malcata, Juliana Sá, Miguel Cabral, Rafael Vasconcelos, Soraia Costa, Inês Morais-Vilaça, Lara Pinheiro-Guedes, João Sarmento, Filipe Costa, Rita Moreira, Fátima Fonseca, Jaime Alves, Marisa Miraldo, Alexandre Morais Nunes, Hutan Ashrafian, Ara Darzi and Fernando Araújo
Healthcare 2025, 13(7), 821; https://doi.org/10.3390/healthcare13070821 (registering DOI) - 4 Apr 2025
Abstract
Background/Objectives: The Portuguese NHS has embarked on an administrative restructuring aimed at enabling healthcare professionals, particularly family doctors, to focus on direct patient care and improve overall healthcare outcomes. This article details these measures, their initial benefits for patients and professionals, and explores
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Background/Objectives: The Portuguese NHS has embarked on an administrative restructuring aimed at enabling healthcare professionals, particularly family doctors, to focus on direct patient care and improve overall healthcare outcomes. This article details these measures, their initial benefits for patients and professionals, and explores future strategies to further integrate levels of care and leverage technology to enhance efficiency, patient-centeredness, and ultimately, population health. Methods: Each measure was evaluated to estimate its potential impact on the four pillars of the value-based healthcare (VBHC) framework. Results: We found that most measures aimed at reducing bureaucracy had an estimated impact on more than two of the four pillars. Conclusions: Thus, we conclude that the reduction in bureaucracy will tend to address several of the pillars of the VBHC framework and should be considered as a steppingstone in the process of increasing VBHC.
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(This article belongs to the Topic Integrated Health Services across Different Levels: Worldwide Experiences)
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Open AccessReview
Patient–Practitioner–Environment Synchronization: Four-Step Process for Integrating Interprofessional and Distinctive Competencies in Osteopathic Practice—A Scoping Review with Integrative Hypothesis
by
Christian Lunghi, Francesca Baroni, Giandomenico D’Alessandro, Giacomo Consorti, Marco Tramontano, Laurent Stubbe, Josie Conte, Torsten Liem and Rafael Zegarra-Parodi
Healthcare 2025, 13(7), 820; https://doi.org/10.3390/healthcare13070820 (registering DOI) - 4 Apr 2025
Abstract
Background. A major goal for a significant portion of the osteopathic community is to update osteopathic principles, satisfying three needs: sourcing from the origin, proposing original and unique practical approaches, and describing the entire process in a scientifically updated way. On this line,
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Background. A major goal for a significant portion of the osteopathic community is to update osteopathic principles, satisfying three needs: sourcing from the origin, proposing original and unique practical approaches, and describing the entire process in a scientifically updated way. On this line, several interprofessional proposals for healthcare providers have already been made by implementing patient-centered care and touch-based strategies informed by the enactive model. Enactivism principles can provide a foundation for rethinking osteopathic care by integrating environmental, psychological, social, and existential factors to facilitate the patient’s biobehavioral synchronization with the environment and social context, address health needs, and enhance the quality of multiprofessional healthcare services. However, there is a need to develop a conceptual model that offers a framework for organizing and interpreting disciplinary knowledge, guiding clinical observation and practical strategies, and defining both interprofessional collaboration and the unique focus of the profession. This scoping review and integrative hypothesis aim to fulfill the need for a more detailed and comprehensive understanding of the distinctive osteopathic care to biobehavioral synchrony, emphasizing both interprofessional collaboration and the profession’s unique competencies. Methods. The present article was developed in accordance with established guidelines for writing biomedical scoping reviews. Results. A total of 36 papers were considered for thematic and qualitative analyses, which supported the integrative hypothesis. Considering the current tenets for osteopathic rational practice, we propose an integrative hypothesis to focus on a practical framework for osteopathic patient biobehavioral synchronization. Patient–practitioner–environment synchronization could be promoted through a four-step process: (1) a narrative-based sense-making and decision-making process; (2) a touch-based shared sense-making and decision-making process; (3) hands-on, mindfulness-based osteopathic manipulative treatment; (4) patient active participatory osteopathic approaches to enhance person-centered care and rational practice. Conclusions and future directions: The proposed model fosters patient–practitioner synchronization by integrating updated traditional osteopathic narratives and body representations into practice, offering a culturally sensitive approach to promoting health, addressing contemporary health needs, and improving inclusive health services. Future studies are required to assess the transferability and applicability of this framework in modern settings worldwide.
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(This article belongs to the Collection Osteopathic and Manual Therapy Healthcare Reconceptualization: Health Needs and New Evidence)
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Open AccessSystematic Review
Occupational Diseases in Art Conservators and Restorers: A Systematic Review
by
Maria R. Ferreira, André V. Brito and Ricardo J. Fernandes
Healthcare 2025, 13(7), 819; https://doi.org/10.3390/healthcare13070819 - 4 Apr 2025
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Background/Objectives: Although cultural heritage conservators and restorers face consistent exposure to a multifaceted range of occupational hazards, research on their health remains limited. This systematic review aims to explore and synthesize the prevalence and types of occupational diseases among conservators and restorers
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Background/Objectives: Although cultural heritage conservators and restorers face consistent exposure to a multifaceted range of occupational hazards, research on their health remains limited. This systematic review aims to explore and synthesize the prevalence and types of occupational diseases among conservators and restorers of cultural heritage. It also intends to map populations, interventions, contexts and other relevant information to assess the current state of knowledge and identify gaps in the literature on the occupational health of conservation and restoration professionals. Methods: The systematic review followed PRISMA 2020 guidelines and the Cochrane handbook. Eligible studies were identified through comprehensive searches of databases, and inclusion criteria were applied to select relevant articles. The protocol was designed according to PRISMA 2020, Prisma-ScR guidelines and the Cochrane handbook. The searches were conducted on 23 May 2024 in PubMed, Scopus and Web of Science (core collection). The risk-of-bias assessment was performed using the Cochrane method for non-randomized studies (RoBANS). Results: Respiratory symptoms were the most prevalent occupational health issue, affecting 28% of cases. General symptoms and abdominal issues each accounted for 20% and 18%, respectively, while musculoskeletal disorders were reported in 14% of cases, primarily affecting the neck, back, shoulders and wrists due to prolonged static postures and repetitive movements. Dermatological and irritation manifestations were reported in 10% of cases. Additionally, 10% of cases involved specific diseases such as pneumonia and cancer. The risk-of-bias assessment revealed significant methodological heterogeneity, with notable gaps in exposure assessment and disease outcome reporting across studies. Conclusions: This analysis highlights the different health risks faced by conservators and restorers of cultural heritage, underscoring the need for standardized methodologies and prospective studies to increase the data on occupational risks.
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Open AccessArticle
Patient Perspectives on the Care in a Long COVID Outpatient Clinic—A Regional Qualitative Analysis from Germany
by
Lea Alexandra Gölz, Regina Poß-Doering, Uta Merle, Michel Wensing and Sandra Stengel
Healthcare 2025, 13(7), 818; https://doi.org/10.3390/healthcare13070818 - 3 Apr 2025
Abstract
Background/Objectives: Long COVID specialized outpatient clinics (sOCs), which are part of the recommended long COVID care, usually face high demand. Few studies focused on the experience of care in such facilities in Germany. This study investigated how patients experience care in a
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Background/Objectives: Long COVID specialized outpatient clinics (sOCs), which are part of the recommended long COVID care, usually face high demand. Few studies focused on the experience of care in such facilities in Germany. This study investigated how patients experience care in a sOC at a German university hospital. Methods: Semi-structured interviews were conducted with patients attending this clinic between October 2022 and January 2023. Data analysis was based on thematic analysis. Results: The themes from interviews with 14 patients (F = 11, M = 3) could be broadly categorized into statements on the pathway to the sOC, and statements on care provided in the sOC. Findings show that patients’ high expectations at the sOC appointment were shaped by previous experiences with care, which were mainly perceived as inadequate. Care in the sOC was predominantly perceived as competent, empathetic and relevant for further care and coping with the disease. A deterioration in health directly related to the consultation (classifiable as post-exertional malaise) was frequently described, as was a high need for ongoing consultation. Conclusions: Overall, the findings point to a need for adaptations in the sOC, such as identifying optimized models of care and tailoring them to the patients’ limited resources. This includes measures to improve care outside the sOC.
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